Rotary evaporators are typically used to remove solvents following chemical reactions. Combined with gentle heat from the evaporator bath, controlled vacuum is used to bring solvents to boiling or near-boiling. Efficient solvent distillation requires vacuum balanced to achieve sufficient pressure reduction and molecular flow without losing sample or overrunning the condensing capabilities of your rotovap. When selecting a vacuum pump for rotary evaporation:
- Select a chemical resistant dry diaphragm vacuum pump for routine evaporations.
- Buy a vacuum pump capable of quickly evaporating your least volatile solvent. Fast stripping of DMF requires a 2 torr diaphragm pump. See Model Selector.
- The ability to adjust vacuum level and react quickly to bumping / foaming conditions are keys to preserving your sample and using your time efficiently.
- Automated diaphragm vacuum systems can help you save both sample and time.